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Giant Cell Tumor of Bone
GENERAL INFORMATION Giant cell tumor (GCT) of bone is a benign but aggressive bone tumor originating from mesenchymal cells. Initially, described by Cooper and Travers in 1818 as an aggressive and destructive lesion of long bones, then Virchow first described the...
Fibrous Dysplasia
GENERAL INFORMATION Fibrous dysplasia is not considered a tumor; it is a developmental disorder of the bone. It appears similar to a tumor on radiological studies. Fibrous dysplasia is caused by the inability of the bone-forming tissue to produce mature bone due to a...
Ewing Sarcoma
General Information Ewing sarcoma is a small round blue cell sarcoma It is a primary osseous neoplasm (cancer/sarcoma) composed of uniform, monotonous, small round blue cells without any matrix production Fourth most common primary malignancy of bone Approximately 5%...
Eosinophilic Granuloma
General Information This is a benign proliferation of Langerhans cells usually accompanied with eosinophils, lymphocytes, neutrophils and scattered plasma cells. There may be solitary or multiple lesions confined to bone 70% of cases consist of a solitary lesion...
Enchondromatosis
General Information Enchondromatosis is enchondral ossification or cartilage dysplasia.Occurs in two clinical disorders: Ollier’s Disease rare skeletal disorder Multifocal intramedullary proliferation of dysplastic cartilage Present in one bone or multiple bones with...
Enchondroma
General Information Enchondroma is a benign indolent intramedullary hyaline cartilage neoplasm Accounts for 10% of all benign osseous tumors Limited growth, most lesions are less than 5 cm in maximal dimension Bones grow from a cartilaginous growth plate that...